Scientific Communications – University of Copenhagen

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BIOCHILD > Scientific Communications

Full-length research articles in peer-reviewed international journals
1. Farpour-Lambert NJ, Baker JL, Hassapidou M, Holm JC, Nowicka P, O’Malley G, Weiss R. Childhood obesity is a chronic disease demanding specific health care. A Position Statement from the Childhood Obesity Task Force of the European Association for the Study of Obesity (EASO). Obes Facts. 2015 Oct 16;8(5):342-349. [Epub ahead of print].

2. Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L; Bone Mineral Density in Childhood Study (BMDCS); Early Genetics and Lifecourse Epidemiology (EAGLE) consortium, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen AL, Haworth CM, Hirschhorn JN, Hofman A, Holm JC, Horikoshi M, Hottenga JJ, Huang J, Kadarmideen HN, Kähönen M, Kiess W, Lakka HM, Lakka TA, Lewin AM, Liang L, Lyytikäinen LP, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfäffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CM, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis GV, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widén E, Boomsma DI, Koppelman GH, Sebert S, Järvelin MR, Hyppönen E, McCarthy MI, Lindi V, Harri N, Körner A, Bønnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sørensen TI, Timpson NJ, Grant SF, Jaddoe VW; Early Growth Genetics (EGG) Consortium; Bone Mineral Density in Childhood Study BMDCS. Genome-wide association analysis identifies three new childhood body mass index susceptibility loci.Human Molecular Genetics 25 (2): 389-403 doi:10.1093/hmg/ddv472

3. Fonvig CE, Chabanova E, Andersson EA, Ohrt JD, Pedersen O, Hansen T, Thomsen HS, Holm JC. 1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents. PLoS ONE. 7. August 2015;10(8):e0135018

4. Fonvig CE, Chabanova E, Ohrt JD, Nielsen LA, Pedersen O, Hansen T, Thomsen HS, Holm JC. Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle. BMC Pediatr. 2015;15:196.

5. Gade C, Christensen HR, Holst H. Lægemiddeldosering til overvægtige børn. Ugeskr Læger 2015;177:V05150446                  

6. Hollensted M/Ahluwalia TS, Have CT, Grarup N, Fonvig CE, Nielsen TRH, Trier C, Paternoster L, Pedersen O, Holm J-C, Sørensen TIA, Hansen T. Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study. BMC Med Genet. 2015;16(1):105.

7. Johansen A, Holm J-C, Pearson S, Kjærsgaard M, Larsen LM, Højgaard B, et al. Danish clinical guidelines for examination and treatment of overweight and obese children and adolescents in a pediatris setting. Dan Med J. 2015 May;62

8. Lausten-Thomsen U, Christiansen M, Fonvig CE, Trier C, Pedersen O, Hansen T, Holm JC. Reference values for serum total adiponectin in healthy non-obese children and adolescents. Clin Chim Acta. 2015 Jul 10;450:11-14. doi: 10.1016/j.cca.2015.07.012.

9. Lausten-Thomsen U, Christiansen M, Hedley PL, Holm JC, Schmiegelow K. Adipokines in umbilical cord blood from children born large for gestational age. J Pediatr Endocrinol Metab. 2015 Jul 18. pii: /j/jpem.ahead-of-print/jpem-2014-0502/jpem-2014-0502.xml. doi: 10.1515/jpem-2014-0502.

10. Lausten-Thomsen U, Gamborg M, Bøjsøe C, Hedley PL, Hagen CM, Christiansen M, Holm JC. Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children. J Pediatr Endocrinol Metab. 2015 Mar 1;28(3-4):393-8. doi: 10.1515/jpem-2014-0249.

11. Most SW, Højgaard B, Teilmann G, Andersen J, Valentiner M, Gamborg M, Holm JC. Adoption of the children’s obesity clinic’s treatment (TCOCT) protocol into another Danish pediatric obesity treatment clinic. BMC Pediatrics. 2015, 15:13. DOI: 10.1186/s12887-015-0332-9

12.Nielsen LA, Bøjsøe C, Kloppenborg JT, Trier C, Gamborg M, Holm JC. The Influence of Familial Predisposition to Cardiovascular Complications upon Childhood Obesity Treatment. PLoS One. 2015.10;10(3):e0120177. doi: 10.1371/journal.pone.0120177. eCollection 2015.

13. Nielsen LA, Nielsen TRH, Holm JC. The Impact of Familial Predisposition to Obesity and Cardiovascular Disease on Childhood Obesity. Obes Facts. 2015 Oct 14;8(5):319-328. [Epub ahead of print].

14. Palleja A, Jensen LJ. HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases. PeerJ. 2015 Jun 30;3:e1057

15. Trier C, Bøjsøe C. Childhood obesity [Overvægt i barnealderen. Danish]. Best Practice. 2015 Okt; 9(9):40-2.

16. Trier C, Fonvig CE, Bøjsøe C, Mollerup PM, Gamborg M, Pedersen O, Hansen T, Holm JC: No influence of sugar, snacks and fast food intake on the degree of obesity or treatment effect in childhood obesity. Pediatr Obes. 2016 Feb 22. doi: 10.1111/ijpo.12094. [Epub ahead of print].

17. Xu H, Zhang H, Yang W, Yadav R, Morrison AC, Qian M, Devidas M, Liu Y, Perez-Andreu V, Zhao X, Gastier-Foster JM, Lupo PJ, Neale G, Raetz E, Larsen E, Bowman WP, Carroll WL, Winick N, Williams R, Hansen T, Holm JC, Mardis E, Fulton R, Pui CH, Zhang J, Mullighan CG, Evans WE, Hunger SP, Gupta R, Schmiegelow K, Loh ML, Relling MV, Yang JJ. Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children.Nat Commun. 2015 Jun 24;6:7553. doi: 10.1038/ncomms8553

18. Kogelman, LJA., Zhernakova, DV., Westra, HJ., Cirera, S., Fredholm, M., Franke, L., Kadarmideen, HN (2015). An integrative systems genetics approach reveals potential causal genes and pathways related to obesity. Genome Medicine 7:105  doi:10.1186/s13073-015-0229-0

19. Pant, S.D., Karlskov-Mortensen, P., Jacobsen, M.J., Cirera, S., Kogelman, L.J.A.,  Bruun, C.S.,  Mark, T., Jørgensen, C.B., Grarup, N., Appel, E.V.R.,  Galjatovic, E.A.A.,  Hansen, T., Pedersen, O.B.,   Guerin, M., Huby, T., Lesnik, P., Meuwissen, T.H.E.,  Kadarmideen, H.N.  and Fredholm, M. (2015). Comparative Analyses of QTLs influencing Obesity and Metabolic Phenotypes in Pigs and Humans. PLoS One  10(9): e0137356. doi:10.1371/journal.pone.0137356

20. Kogelman, L.J.A., S. Cirera, D.V. Zhernakova, M. Fredholm, L. Franke, H.N. Kadarmideen. 2014. Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model. BMC Medical Genomics 7: 57. http://www.biomedcentral.com/1755-8794/7/57. doi:10.1186/1755-8794-7-57. 16 pp.

21. Kogelman, L.J.A., Pant,S.D., Fredholm, M., Kadarmideen, H.N. (2014). Systems genetics of obesity in an F2 pig model by genome-wide association, genetic network and pathway analyses. Frontiers in Genetics (Systems biology), 5:214. doi: 10.3389/fgene.2014.00214

22. Kogelman, LJA and Kadarmideen, HN. (2014). Weighted Interaction SNP Hub (WISH) network method for building genetic networks for complex diseases using whole genome genotype data. BMC Systems Biology 8(Suppl 2): S5 (http://www.biomedcentral.com/1752-0509/8/S2/S5)

23. Kogelman, L.J.A., H.N. Kadarmideen, T. Mark, P. Karlskov-Mortensen, C. S. Bruun, S. Cirera, M.J. Jacobsen, C.B. Jørgensen and M. Fredholm (2013). An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters. Frontiers in Genetics 4:29. Doi:10.3389/fgene.2013.00029

Conference papers

1. Kogelman, L.J.A.,Bonder, M-J., Franke, L., and H.N. Kadarmideen. 2015. Gene co-expression networks within and across tissues in morbidly obese individuals. Proceedings of the Workshop on Statistical Methods for Omics Data Integration and Analysis, 14-16 September 2015, Principe Felipe Research Center, Valencia, Spain.

2. L.J.A. Kogelman, S.D. Pant, J. Karjalainen, L. Franke, M. Fredholm, H.N. Kadarmideen. Systems genetics analysis of obesity in a porcine model using WISH network method. Proceedings of 10th World Congress of Genetics Applied to Livestock Production (WCGALP), 16-23 August 2014, Vancouver, British Columbia, Canada. Paper number: 9004

2. L.J.A. Kogelman, D.V. Zhernakova, H-J. Westra, S. Cirera, M. Fredholm, L. Franke, H.N. Kadarmideen. Systems genetics analysis of obesity using RNA-Seq data in an F2 pig ressource population. Proceedings of 10th World Congress of Genetics Applied to Livestock Production (WCGALP), 16-23 August 2014, Vancouver, British Columbia, Canada. Paper number: 8987

Abstracts/short papers

1. L.J.A. Kogelman, D.V. Zhernakova, H-J. Westra, S. Cirera, M. Fredholm, L. Franke, H.N. Kadarmideen. Systems genetics analysis of RNA-Seq data to unravel the genetics of obesity using a porcine model. Proceedings of the Annual meeting of the European Federation of Animal Science, Copenhagen, Denmark, 25-29 August 2014.

2. L.J.A. Kogelman, S.D. Pant, J. Karjalainen, L. Franke, M. Fredholm, H.N. Kadarmideen. The WISH network method applied to obesity in an F2 pig population. Proceedings of the Annual meeting of the European Federation of Animal Science, Copenhagen, Denmark, 25-29 August 2014.

3. Frederiksen,S.D., S.D. Pant, L.J.A. Kogelman, M. Fredholm, H. N. Kadarmideen. 2014. Quantitative and Systems Genetics Analyses of Lipid Profiles in a Pig Model for Obesity. Proceedings of the Annual meeting of the European Federation of Animal Science, Copenhagen, Denmark, 25-29 August 2014. Abstract no.: 19049.

4. Mantas, P., Kogelman, L.J.A., Cirera, S., Fredholm, M., Kadarmideen, H.N. 2014. Systems biology and RNA-Seq analyses to detect biomarkers for metabolic syndrome in a porcine model. Proceedings of the Annual meeting of the European Federation of Animal Science, Copenhagen, Denmark, 25-29 August 2014. Abstract no.: 19050

5. Kogelman, LJA, M. Fredholm, and H.N. Kadarmideen (2013). A systems genetics analysis of obesity using the Weighted Interaction SNP Hub (WISH) network method. Proceedings of the 14th International Conference on Systems Biology, Copenhagen, 30 August – 3 September 2013

6. Kogelman, L. J. A. and H.N. Kadarmideen. 2013. The Weighted Interaction SNP Hub (WISH) network method for systems genetics analyses. Annual meeting of the European Federation of Animal Science, Nantes, 26-30 August 2013

7. L.J.A. Kogelman, D.V. Zhernakova, H-J. Westra, S. Cirera, M. Fredholm, L. Franke, H.N. Kadarmideen. Systems genetics approaches to integrate genomic and transcriptomics data in a porcine model for human obesity. PhD Day SUND, University of Copenhagen, May 2014, Copenhagen, Denmark

8. L.J.A. Kogelman, M. Fredholm, H.N. Kadarmideen. A systems genetics analysis of obesity using the Weighted Interaction SNP Hub (WISH) network method. 7th Annual International SHARE Symposium, Nov 2013, Copenhagen, Denmark

9. Kogelman, L. J. A. and H.N. Kadarmideen. 2013. Weighted Interaction SNP Hub (WISH) network method for building genetic networks using high-throughput genotype data. Proceedings of the Genomics in Metabolism Conference, Nov 3-6, Helsingor, Denmark

10. Kogelman L.J.A., D. Zhernakova, H-J. Westra, S. Cirera, M. Fredholm, L. Franke, H.N.Kadarmideen. Systems genetics analysis of obesity using RNA-Seq data. Proceedings of the Genomics in Metabolism Conference, Nov 3-6, Elsinore, Denmark

11. Kadarmideen, HN., Pant,SD., Karlskov-Mortensen, P., Kogelman, LJA., Cirera, S., Jacobsen, MJ., Bruun,CS., Mark, T., Jørgensen, CB., Meuwissen THE., and Fredholm. M. 2013. The pig as a model for studies of genomics of obesity and obesity related metabolic diseases. Proceedings of the Genomics in Metabolism Conference, Nov 3-6, Elsinore, Denmark

12. Kogelman L.J.A, S. Horvath, M. Fredholm and H.N. Kadarmideen. 2013. The Weighted Interaction SNP Hub (WISH) Network for systems genetics analysis of obesity. PhD Day SUND, University of Copenhagen, May 2013, Copenhagen, Denmark

13. Kogelman, L. J. A., S. Pant, S. Horvath, M. Fredholm, H. N. Kadarmideen. 2013. Pathway profiling of obesity using the weighted interaction SNP hub (WISH) network method. The Joint Human Genetics Meeting 2013 and the 21st International Congress of Genetics, Singapore, 13-18 April, 2013

14. Jacobsen, M., CM Junker, LJA Kogelman, T Mark, P Karlskov-Mortensen, CS Bruun, S Cirera, J Gorodkin, HN Kadarmideen, R Barres, CB Jørgensen and M Fredholm. 2013. Global Analysis of Genetic and Epigenetic differences associated with obesity. Proceedings of the Keystone Symposia on “Adipose tissue Biology and Diabetes”, Keystone Resort, Keystone, Colorado, USA, January 27—Feb 1, 2013

15. Kogelman, LJA, Kadarmideen, H.N., Mark, T, Karlskov-Mortensen, P., Bruun, C.S., Cirera, S., Jacobsen, M.J., Jørgensen, C.B. and Fredholm, M. 2012.An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: Design and genetic parameters. Symposium SHARE – Synergy in Human and Animal Research, Nov 2012, Copenhagen, Denmark.

16. Kogelman, L.J.A, Kadarmideen, H.N., Mark, T, Karlskov-Mortensen, P., Bruun, C.S., Cirera, S., Jacobsen, M.J., Jørgensen, C.B. and Fredholm, M. 2012. An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: Design and genetic parameters. UNIK Symposium, Nov 2012, Copenhagen, Denmark.

17. Kogelman, L.J.A., Mark, T. Karlskov-Mortensen, P., Bruun, CS., Cirera, S., Jørgensen, C.B., Fredholm, M., and Kadarmideen, H.N. 2012. Genetic parameters for fatness-related traits in pigs: animal model for human obesity. The 4th International Conference of Quantitative Genetics: Understanding Variation in Complex Traits, 17 – 22 Jun 2012, Edinburgh, UK, P0344